Download the complete Mitosol Kit informational package.
This video package contains the step-by-step instructional guide for properly using Mitosol. It includes 4 short video segments which break down the entire process.
- Getting Started
- Reconstituting Mitosol
- Preparing Pledget Sponges
- Using Mitosol
Mitosol Inservice Video Transcript
The contents inside the white outer pack are sterile. This pack should be handled, opened and it’s contents dispensed by a circulating nurse.
The contents of the white outer pack include the package insert, instructions for use, which should be read prior to use, a Ziploc chemotherapy waste bag, and a sterile inner tray. The sterile inner tray contains the procedural components needed to reconstitute and use Mitosol.
The sterile inner tray and its contents are sterile and therefore must be handled, opened and it’s contents assembled and dispensed by a sterile scrub person.
Opening the sterile inner tray, we can see the following. The Mitosol vial and a vial adapter with spike within a foam pouch, a 1mL syringe of sterile water for injection, a plunger rod, a safety connector, a sponge container with pre-cut sponges and a 1mL lure lock TB syringe.
Before the reconstitution of Mitosol, it is recommended that you prepare the sponge tray. To do so, remove the sponge container with precut sponges and TB syringe from the inner tray. Dump the pre-cut sponges back into the inner tray. Select the surgeon preferred sponges and place back into the sponge tray. Close the lid, attach the luer lock TB syringe to one side of the sponge tray and set aside while you reconstitute the Mitosol.
To safely reconstitute the Mitosol, the sterile scrub technician should perform the following steps
First, remove the plunger rod and the prefilled syringe from the sterile tray.
Next, screw the plunger rod into the plunger of the prefilled syringe.
Snap the protective cap from the tip of the syringe. Do not twist the cap.
Attach the safety connector to the prefilled syringe by screwing the safety connector until firmly seated.
Remove the Mitosol vial and vial adapter from the blue foam pouch.
Press and Screw the vial adapter to the safety connector until firmly seated.
Place the vial on a flat surface, push the syringe and vial adapter down to spike the Mitosol drug vial and then inject the sterile water down into the vial. Invert and shake well to insure complete drug reconstitution. Once the Mitosol is reconstituted it is now time to soak the sponges.
Preparing Pledget Sponges
The sterile scrub tech will invert the vial, and draw the full volume of medication into the syringe.
Unscrew the vial adapter from the safety connector. Make sure that the vial adapter remains on the vial.
Screw the syringe that contains the Mitosol into the sponge tray on the end opposite of the already attached TB syringe.
Inject the full volume of the medication into the sponge container to saturate the sponges. Wait 60 seconds allowing for the Mitosol to be fully absorbed by the sponges.
After waiting 60 seconds, any excess fluid within the container can be removed by withdrawing the plunger of the TB syringe.
The Mitosol is now ready for use by the surgeon. It must be used within 1 hour of reconstitution.
The surgeon will now apply the saturated sponges to the surgical site. The sponges will be left on the eye for 2 minutes.
After the allotted time has passed, the surgeon will remove the sponges and place them back into the container and close the lid.
The entire assembly will be placed into the chemotherapy waste disposal bag and the process is complete.